Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, United States. Section of Heart Failure and Cardiac Transplantation, The Cleveland Clinic, Cleveland, OH, United States. Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, United States; Program of Applied Translational Research, Yale University School of Medicine, New Haven, CT, United States. Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY, United States. Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States. Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, United States. Electronic address: jeffrey.testani@yale.edu.